Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy–Associated Cardiomyopathy

Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy–Associated Cardiomyopathy

Background Duchenne muscular dystrophy is a fatal cardiac and skeletal muscle disease resulting from mutations in the dystrophin gene. We have previously demonstrated that a dystrophin‐associated protein, sarcospan (SSPN), ameliorated Duchenne muscular dystrophy skeletal muscle degeneration by activ...

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Bibliographic Details
Main Authors: Michelle S. Parvatiyar, Jamie L. Marshall, Reginald T. Nguyen, Maria C. Jordan, Vanitra A. Richardson, Kenneth P. Roos, Rachelle H. Crosbie‐Watson
Format: Article
Language:English
Published: Wiley 2015-12-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiac hypertrophy
cell adhesion molecules
Duchenne muscular dystrophy
gene therapy
Online Access:https://doi.org/10.1161/JAHA.115.002481

Internet

https://doi.org/10.1161/JAHA.115.002481

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