Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production

Developmental Vitamin D Availability Impacts Hematopoietic Stem Cell Production

Vitamin D insufficiency is a worldwide epidemic affecting billions of individuals, including pregnant women and children. Despite its high incidence, the impact of active vitamin D3 (1,25(OH)D3) on embryonic development beyond osteo-regulation remains largely undefined. Here, we demonstrate that 1,2...

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Bibliographic Details
Main Authors: Mauricio Cortes, Michael J. Chen, David L. Stachura, Sarah Y. Liu, Wanda Kwan, Francis Wright, Linda T. Vo, Lindsay N. Theodore, Virginie Esain, Isaura M. Frost, Thorsten M. Schlaeger, Wolfram Goessling, George Q. Daley, Trista E. North
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Cell Reports
Subjects:
vitamin D
1,25(OH)D3
hematopoietic stem cell (HSC)
cxcl8
zebrafish
hUCB
CFU-C
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716312177

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http://www.sciencedirect.com/science/article/pii/S2211124716312177

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