Stereotactic Injection of DTI-015 into Recurrent Malignant Gliomas: Phase I/II Trial

DTI-015 (BCNU in 100% ethanol) utilizes solvent facilitated perfusion for the intratumoral treatment of gliomas. The ethanol solvent vehicle facilitates a rapid and thorough saturation of the tumor with the dissolved anticancer agent BCNU. We conducted a phase I/II dose escalation study of DTI-015...

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Bibliographic Details
Main Authors: Samuel J. Hassenbusch, Emilio M. Nardone, Victor A. Levin, Norman Leeds, Dennis Pietronigro
Format: Article
Language:English
Published: Elsevier 2003-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
GBM
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860380012X