A novel pancreatic tumour and stellate cell 3D co-culture spheroid model

Abstract Background Pancreatic ductal adenocarcinoma is a devastating disease with poor outcome, generally characterized by an excessive stroma component. The purpose of this study was to develop a simple and reproducible in vitro 3D-assay employing the main constituents of pancreatic ductal adenoca...

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Main Authors: K. J. Norberg, X. Liu, C. Fernández Moro, C. Strell, S. Nania, M. Blümel, A. Balboni, B. Bozóky, R. L. Heuchel, J. M. Löhr
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-020-06867-5