Closed-Loop Control of a Fragile Network: Application to Seizure-like Dynamics of an Epilepsy Model

It has recently been proposed that the epileptic cortex is fragile in the sense that seizures manifest through small perturbations in the synaptic connections that render the entire cortical network unstable. Closed-loop therapy could therefore entail detecting when the network goes unstable from sp...

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Bibliographic Details
Main Authors: Daniel eEhrens, Duluxan eSritharan, Sridevi V. Sarma
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00058/full