Relevance of physicochemical properties and functional pharmacology data to predict the clinical safety profile of direct oral anticoagulants

Abstract Direct oral anticoagulants (DOACs) have rapidly become the drug class of choice for anticoagulation therapy in secondary care. It is known that gastrointestinal hemorrhage are potential side effects of the DOAC drug class. In this study we have investigated the relevance of molecular struct...

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Bibliographic Details
Main Authors: Charles J. Ferro, Fay Solkhon, Zahraa Jalal, Abdullah M. Al‐Hamid, Alan M. Jones
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.603