Relevance of physicochemical properties and functional pharmacology data to predict the clinical safety profile of direct oral anticoagulants
Abstract Direct oral anticoagulants (DOACs) have rapidly become the drug class of choice for anticoagulation therapy in secondary care. It is known that gastrointestinal hemorrhage are potential side effects of the DOAC drug class. In this study we have investigated the relevance of molecular struct...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-06-01
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Series: | Pharmacology Research & Perspectives |
Subjects: | |
Online Access: | https://doi.org/10.1002/prp2.603 |