Identification of small molecules with type I interferon inducing properties by high-throughput screening.

The continuous emergence of virus that are resistant to current anti-viral drugs, combined with the introduction of new viral pathogens for which no therapeutics are available, creates an urgent need for the development of novel broad spectrum antivirals. Type I interferon (IFN) can, by modulating t...

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Bibliographic Details
Main Authors: Luis Martínez-Gil, Juan Ayllon, Mila Brum Ortigoza, Adolfo García-Sastre, Megan L Shaw, Peter Palese
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3492183?pdf=render