Bovine milk-derived exosomes enhance goblet cell activity and prevent the development of experimental necrotizing enterocolitis.

Necrotizing enterocolitis (NEC) is characterized by intestinal injury and impaired mucin synthesis. We recently showed that breast milk exosomes from rodents promote intestinal cell viability, epithelial proliferation, and stem cell activity, but whether they also affect mucus production is unknown....

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Bibliographic Details
Main Authors: Bo Li, Alison Hock, Richard Y Wu, Adam Minich, Steven R Botts, Carol Lee, Lina Antounians, Hiromu Miyake, Yuhki Koike, Yong Chen, Augusto Zani, Philip M Sherman, Agostino Pierro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0211431