Injury to the Endothelial Surface Layer Induces Glomerular Hyperfiltration Rats with Early-Stage Diabetes

Glomerular endothelial surface layer (ESL) may play a role in the mechanisms of albuminuria in diabetic nephropathy, which lack evidence in vivo. The effects of high glucose on the passage of albumin across the glomerular ESL were analysed in streptozotocin-induced diabetic Sprague-Dawley rats for 4...

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Bibliographic Details
Main Authors: Chunyang Zhang, Yao Meng, Qi Liu, Miao Xuan, Lanyu Zhang, Bo Deng, Keqin Zhang, Zhimin Liu, Tao Lei
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2014/953740