Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing

Age of ovarian cancer diagnosis among BRIP1, RAD51C, and RAD51D mutation carriers identified through multi-gene panel testing

Abstract Background Professional society guidelines recommend risk-reducing salpingo-oophorectomy (RRSO) for women with pathogenic variants (PVs) in ovarian cancer-risk genes. Personalization of that intervention is based on gene-specific phenotypes; however, the age of ovarian cancer diagnosis in w...

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Bibliographic Details
Main Authors: Shelly Cummings, Susana San Roman, Jennifer Saam, Ryan Bernhisel, Krystal Brown, Johnathan M. Lancaster, Lydia Usha
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Pan-cancer panel
Genetic testing
Hereditary ovarian cancer
Online Access:https://doi.org/10.1186/s13048-021-00809-w

Internet

https://doi.org/10.1186/s13048-021-00809-w

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