Expression of Gαq Is Decreased in Lymphocytes from Primary Sjögren’s Syndrome Patients and Related to Increased IL-17A Expression

Primary Sjögren’s syndrome (pSS) is a rheumatic disease characterized by the destruction of salivary and lacrimal glands, and its pathogenesis mechanism remains unclear. Gαq is the α-subunit of the heterotrimeric Gq protein. Researches demonstrated that Gαq was involved in the pathogenesis regulatio...

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Bibliographic Details
Main Authors: Yuechi Sun, Ying Wang, Shiju Chen, Guihua Fan, Junhui Zhang, Fan Dai, Hongyan Qian, Yuan Liu, Guixiu Shi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/8212641