Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet

Microglial and peripheral immune priming is partially sexually dimorphic in adolescent mouse offspring exposed to maternal high-fat diet

Abstract Background Maternal nutrition is critical for proper fetal development. While increased nutrient intake is essential during pregnancy, an excessive consumption of certain nutrients, like fat, can lead to long-lasting detrimental consequences on the offspring. Animal work investigating the c...

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Bibliographic Details
Main Authors: Maude Bordeleau, Chloé Lacabanne, Lourdes Fernández de Cossío, Nathalie Vernoux, Julie C. Savage, Fernando González-Ibáñez, Marie-Ève Tremblay
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Neuroinflammation
Subjects:
Hippocampus
Immune priming
Maternal high-fat diet
Microglia
Sex difference
Online Access:http://link.springer.com/article/10.1186/s12974-020-01914-1

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http://link.springer.com/article/10.1186/s12974-020-01914-1

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