Avian influenza virus H5N1 induces rapid interferon-beta production but shows more potent inhibition to retinoic acid-inducible gene I expression than H1N1 in vitro

<p>Abstract</p> <p>Background</p> <p>The mechanisms through which the avian influenza virus H5N1 modulate the host’s innate immune defense during invasion, remains incompletely understood. RIG-I as a pattern recognition receptor plays an important role in mediating inna...

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Bibliographic Details
Main Authors: Mi Zhiqiang, Ma Yonghong, Tong Yigang
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Virology Journal
Subjects:
Online Access:http://www.virologyj.com/content/9/1/145