Electrophysiological effects of polyethylene glycol modified gold nanoparticles on mouse hippocampal neurons

Electrophysiological effects of polyethylene glycol modified gold nanoparticles on mouse hippocampal neurons

Gold nanoparticles (AuNPs) can cross the blood brain barrier, thus can be used as nanocarriers in brain drug delivery. However, the effect of bare and polyethylene glycol-modified (PEGylated) AuNPs on normal neural function has not been extensively investigated. In this study, bioelectrical properti...

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Bibliographic Details
Main Authors: Bilge Guvenc Tuna, Gamze Yesilay, Yavuz Yavuz, Bayram Yilmaz, Mustafa Culha, Akif Maharramov, Soner Dogan
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Heliyon
Subjects:
Gold nanoparticles
Polyethylene glycol
Action potential
Functional neurotoxicity
Electrophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844020326669

Internet

http://www.sciencedirect.com/science/article/pii/S2405844020326669

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