Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids
<p>Abstract</p> <p>Background</p> <p>Expression of P-glycoprotein (P-gp), the multidrug resistance (MDR) 1 gene product, can lead to multidrug resistance in tumours. However, the physiological role of P-gp in tumours growing as multicellular spheroids is not well unders...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-07-01
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| Series: | Cancer Cell International |
| Subjects: | |
| Online Access: | http://www.cancerci.com/content/5/1/20 |