Deep brain stimulation restores the glutamatergic and GABAergic synaptic transmission and plasticity to normal levels in kindled rats.

BACKGROUND:The precise effect of low frequency stimulation (LFS) as a newly postulated, anticonvulsant therapeutic approach on seizure-induced changes in synaptic transmission has not been completely determined. HYPOTHESIS:In this study, the LFS effect on impaired, synaptic plasticity in kindled rat...

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Bibliographic Details
Main Authors: Samireh Ghafouri, Yaghoub Fathollahi, Saeed Semnanian, Amir Shojaei, Azam Asgari, Azin Ebrahim Amini, Javad Mirnajafi-Zadeh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0224834