Acute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats

Acute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats

Abstract Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated. In acute toxicity tests, mice were administered total alkaloids (TA) and five in...

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Bibliographic Details
Main Authors: Yun-Li Zhao, Min Su, Jian-Hua Shang, Xia Wang, Guy Sedar Singor Njateng, Guang-Lei Bao, Jia Ma, Qing-Di Sun, Fang Yuan, Jing-Kun Wang, Xiao-Dong Luo
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:Natural Products and Bioprospecting
Subjects:
Alstonia scholaris
Indole alkaloids
Acute toxicity
Chronic toxicity
Non-observed-adverse-effect-level
Online Access:https://doi.org/10.1007/s13659-020-00237-1

Internet

https://doi.org/10.1007/s13659-020-00237-1

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