Evolution of H9N2 avian influenza virus in embryonated chicken eggs with or without homologous vaccine antibodies

Evolution of H9N2 avian influenza virus in embryonated chicken eggs with or without homologous vaccine antibodies

Abstract Background Vaccines constitute a unique selective pressure, different from natural selection, drives the evolution of influenza virus. In this study, A/Chicken/Shanghai/F/1998 (H9N2) was continually passaged in specific pathogen-free embryonated chicken eggs with or without selective pressu...

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Bibliographic Details
Main Authors: Haiyun Jin, Wan Wang, Xueqin Yang, Hailong Su, Jiawen Fan, Rui Zhu, Shifeng Wang, Huoying Shi, Xiufan Liu
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Veterinary Research
Subjects:
H9N2 influenza virus
Selective pressure of antibody
Mutation
Antigenic drift
Replication
Online Access:http://link.springer.com/article/10.1186/s12917-018-1391-6

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http://link.springer.com/article/10.1186/s12917-018-1391-6

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