The Mitochondrial Chaperone TRAP1 as a Candidate Target of Oncotherapy

The Mitochondrial Chaperone TRAP1 as a Candidate Target of Oncotherapy

Tumor necrosis factor receptor-associated protein 1 (TRAP1), a member of the heat shock protein 90 (Hsp90) chaperone family, protects cells against oxidative stress and maintains mitochondrial integrity. To date, numerous studies have focused on understanding the relationship between aberrant TRAP1...

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Bibliographic Details
Main Authors: Shulan Xie, Xuanwei Wang, Shuyuan Gan, Xiaodong Tang, Xianhui Kang, Shengmei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Oncology
Subjects:
tumor necrosis factor receptor-associated protein 1
tumorigenesis
metabolic reprogramming
apoptosis resistance
inhibitors
cancer therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.585047/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.585047/full

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