Defects in expression of genes related to synaptic vesicle traffickingin frontal cortex of Alzheimer’s disease

Loss of synapses correlates with cognitive decline in Alzheimer’s disease (AD). However, molecular mechanisms underlying the synaptic dysfunction and loss are not well understood. In this study, microarray analysis of brain tissues from five AD cases revealed a reduced expression of a group of relat...

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Bibliographic Details
Main Authors: Pamela J Yao, Min Zhu, Eunice I Pyun, Andrew I Brooks, Stavros Therianos, Victoria E Meyers, Paul D Coleman
Format: Article
Language:English
Published: Elsevier 2003-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102000098