Vitamin D ameliorates adipose browning in chronic kidney disease cachexia

Vitamin D ameliorates adipose browning in chronic kidney disease cachexia

Abstract Patients with chronic kidney disease (CKD) are often 25(OH)D3 and 1,25(OH)2D3 insufficient. We studied whether vitamin D repletion could correct aberrant adipose tissue and muscle metabolism in a mouse model of CKD-associated cachexia. Intraperitoneal administration of 25(OH)D3 and 1,25(OH)...

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Main Authors: Wai W. Cheung, Wei Ding, Hal M. Hoffman, Zhen Wang, Sheng Hao, Ronghao Zheng, Alex Gonzalez, Jian-Ying Zhan, Ping Zhou, Shiping Li, Mary C. Esparza, Richard L. Lieber, Robert H. Mak
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-70190-z

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https://doi.org/10.1038/s41598-020-70190-z

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