Edema toxin impairs anthracidal phospholipase A2 expression by alveolar macrophages.

Bacillus anthracis, the etiological agent of anthrax, is a spore-forming gram-positive bacterium. Infection with this pathogen results in multisystem dysfunction and death. The pathogenicity of B. anthracis is due to the production of virulence factors, including edema toxin (ET). Recently, we estab...

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Bibliographic Details
Main Authors: Benoit Raymond, Dominique Leduc, Lucas Ravaux, Ronan Le Goffic, Thomas Candela, Michel Raymondjean, Pierre Louis Goossens, Lhousseine Touqui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-12-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2134952?pdf=render