Structural Basis of SARS-CoV-2 Polymerase Inhibition by Favipiravir

Summary: The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has developed into an unprecedented global pandemic. Nucleoside analogs, such as Remdesivir and Favipiravir, can serve as the first-line broad-spectrum antiviral drugs by targeting the viral polymerases. However, t...

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Bibliographic Details
Main Authors: Qi Peng, Ruchao Peng, Bin Yuan, Min Wang, Jingru Zhao, Lifeng Fu, Jianxun Qi, Yi Shi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:The Innovation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666675821000059