The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin.

The structure of tumor endothelial marker 8 (TEM8) extracellular domain and implications for its receptor function for recognizing anthrax toxin.

Anthrax toxin, which is released from the gram-positive bacterium Bacillus anthracis, is composed of three proteins: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds a receptor on the surface of the target cell and further assembles into a homo-heptameric pore through whi...

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Bibliographic Details
Main Authors: Sheng Fu, Xiaohang Tong, Chenguang Cai, Ying Zhao, Yang Wu, Yuanyuan Li, Junjie Xu, Xuejun C Zhang, Long Xu, Wei Chen, Zihe Rao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2887854?pdf=render

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http://europepmc.org/articles/PMC2887854?pdf=render

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