MMP3 Is a Non-invasive Biomarker of Rejection in Skin-Bearing Vascularized Composite Allotransplantation: A Multicenter Validation Study

MMP3 Is a Non-invasive Biomarker of Rejection in Skin-Bearing Vascularized Composite Allotransplantation: A Multicenter Validation Study

Background: There is unmet need for non-invasive immunomonitoring to improve diagnosis and treatment of acute rejection in vascularized composite allotransplantation (VCA). Circulating matrix metalloproteinase 3 (MMP3) was described as a candidate non-invasive biomarker to predict treatment response...

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Bibliographic Details
Main Authors: Branislav Kollar, Audrey Uffing, Thiago J. Borges, Andrey V. Shubin, Bruno T. Aoyama, Céline Dagot, Valentin Haug, Martin Kauke, Ali-Farid Safi, Simon G. Talbot, Emmanuel Morelon, Stéphanie Dakpe, Bohdan Pomahac, Leonardo V. Riella
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
acute rejection
biomarker
face transplantation
hand transplantation
vascularized composite allotransplantation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02771/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02771/full

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