CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72.
NK cells are able to kill tumor and virus-infected cells without the need of prior antigen stimulation. The killing of these target cells is regulated by inhibitory, lysis and co-stimulatory receptors that are expressed on the surface of NK cells.CD100 (Semaphorin 4D), a 150kD transmembrane protein,...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-09-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC1950564?pdf=render |