Network hubs affect evolvability.

The regulatory processes in cells are typically organized into complex genetic networks. However, it is still unclear how this network structure modulates the evolution of cellular regulation. One would expect that mutations in central and highly connected modules of a network (so-called hubs) would...

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Bibliographic Details
Main Authors: Jana Helsen, Jens Frickel, Rob Jelier, Kevin J Verstrepen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000111