Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression

Mouse models and genetically engineered mouse models (GEMM) are essential experimental tools for the understanding molecular mechanisms within complex biological systems. GEMM are especially useful for inferencing phenocopy information to genetic human diseases such as breast cancer. Human breast ca...

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Bibliographic Details
Main Authors: Hidetoshi Mori, Robert D. Cardiff, Alexander D. Borowsky
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcell.2018.00035/full