Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data

<p>Abstract</p> <p>Background</p> <p>ChIP-chip data are routinely used to identify transcription factor binding targets. However, the presence of false positives and false negatives in ChIP-chip data complicates and hinders analyses, especially when the binding targets...

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Bibliographic Details
Main Authors: Zhao Hongyu, Datta Debayan
Format: Article
Language:English
Published: BMC 2009-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/23