Structural basis of self-assembly in the lipid-binding domain of mycobacterial polar growth factor Wag31

Structural basis of self-assembly in the lipid-binding domain of mycobacterial polar growth factor Wag31

Wag31, or DivIVA, is an essential protein and a drug target in the human pathogen Mycobacterium tuberculosis that self-assembles at the negatively curved membrane surface to form a higher-order structural scaffold, maintains rod-shaped cellular morphology and localizes key cell-wall synthesizing enz...

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Bibliographic Details
Main Authors: Komal Choukate, Barnali Chaudhuri
Format: Article
Language:English
Published: International Union of Crystallography 2020-07-01
Series:IUCrJ
Subjects:
mycobacterial polar growth
dimer assembly
mycobacterium tuberculosis
coiled coil
lipids
filaments
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2052252520006053

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http://scripts.iucr.org/cgi-bin/paper?S2052252520006053

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