The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity

The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity

<p>Abstract</p> <p>Background</p> <p>Plasminogen activator inhibitor type-2 (PAI-2, SERPINB2) is an irreversible, specific inhibitor of the urokinase plasminogen activator (uPA). Since overexpression of uPA at the surface of cancer cells is linked to malignancy, targeti...

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Bibliographic Details
Main Authors: Vine Kara L, Gunawardhana Lakshitha P, Cochran Blake J, Lee Jodi A, Lobov Sergei, Ranson Marie
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/9/43

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http://www.biomedcentral.com/1472-6750/9/43

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