Design, Synthesis and Antitumor Activity of Novel 4-Methyl-(3'S,4'S)-cis-khellactone Derivatives

An asymmetric synthesis of a series of novel 4-methyl-(3'S,4'S)-cis-khellactone derivatives 3a–o is reported for the first time. Their structures were confirmed by 1H-NMR, 13C-NMR and MS. Their cytotoxic activity was evaluated by the MTT assay against three selected human cancer ce...

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Bibliographic Details
Main Authors: Taigang Liang, Qingshan Li, Chaoqun Yan, Mengnan Hu, Xue Du, Luhui Ren
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/4/4158