Epigenetic modification enzymes: catalytic mechanisms and inhibitors
Epigenetic modifications alter chromatin structures and consequently affect transcription and cellular functions. Major epigenetic markers include DNA methylation and histone acetylation and methylation. The modifications are reversible and are achieved in aid of relative enzymes. Much effort has be...
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| Format: | Article |
| Language: | English |
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Elsevier
2013-05-01
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| Series: | Acta Pharmaceutica Sinica B |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383513000397 |