ARC regulates programmed necrosis and myocardial ischemia/reperfusion injury through the inhibition of mPTP opening

Necrosis is a key factor in myocardial injury during cardiac pathological processes, such as myocardial infarction (MI), ischemia/reperfusion (I/R) injury and heart failure. Increasing evidence suggests that several aspects of necrosis are programmed and tightly regulated, so targeting the necrosis...

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Bibliographic Details
Main Authors: Tao Xu, Wei Ding, Xiang Ao, Xianming Chu, Qinggong Wan, Yu Wang, Dandan Xiao, Wanpeng Yu, Mengyang Li, Fei Yu, Jianxun Wang
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231718305585