Action of trichostatin A on Alzheimer’s disease-like pathological changes in SH-SY5Y neuroblastoma cells

Action of trichostatin A on Alzheimer’s disease-like pathological changes in SH-SY5Y neuroblastoma cells

The histone deacetylase inhibitor, trichostatin A, is used to treat Alzheimer’s disease and can improve learning and memory but its underlying mechanism of action is unknown. To determine whether the therapeutic effect of trichostatin A on Alzheimer’s disease is associated with the nuclear factor er...

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Bibliographic Details
Main Authors: Li-Hua Li, Wen-Na Peng, Yu Deng, Jing-Jing Li, Xiang-Rong Tian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Neural Regeneration Research
Subjects:
Alzheimer’s disease; amyloid-β peptide; autophagy; Keap1 signal; neurocytotoxicity; oxidative stress damage; SH-SY5Y cells; total antioxidant capacity; transcription factor Nrf2; TSA
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=293;epage=301;aulast=Li

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2020;volume=15;issue=2;spage=293;epage=301;aulast=Li

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