Enhanced osteogenesis and therapy of osteoporosis using simvastatin loaded hybrid system

Enhanced osteogenesis and therapy of osteoporosis using simvastatin loaded hybrid system

Postmenopausal osteoporosis is a common chronic dynamic bone disorder, caused by estrogen deficiency. To address this issue, we constructed a controlled drug-release system composed of poly (N-isopropylacrylamide) brush modified mesoporous hydroxyapatite (MHA-SIM-P) loaded with simvastatin (SIM) usi...

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Bibliographic Details
Main Authors: Tao Wu, Jing Sun, Lei Tan, Qi Yan, Lei Li, Liangwen Chen, Xiangmei Liu, Shi Bin
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Bioactive Materials
Subjects:
Osteogenesis
Osteoporosis
Mesoporous hydroxyapatite
Bone marrow stromal cells
Drug release
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X2030044X

Internet

http://www.sciencedirect.com/science/article/pii/S2452199X2030044X

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