Common genetic signatures of Alzheimer’s disease in Down Syndrome [version 1; peer review: 2 approved]
Background: People with Down Syndrome (DS) are born with an extra copy of Chromosome (Chr) 21 and many of these individuals develop Alzheimer’s Disease (AD) when they age. This is due at least in part to the extra copy of the APP gene located on Chr 21. By 40 years, most people with DS have amyloid...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
F1000 Research Ltd
2020-11-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/9-1299/v1 |