Differences in pharmacology of tumor necrosis factor (TNF) antagonists

The commercially available inhibitors of TNF are constituted by two classes of molecules: the soluble receptors (Etanercept: Amgen Inc. Wyeth) and the monoclonal antibodies (Adalimumab: Abbott Laboratories and Infliximab: Centocor, Inc.). The differences in their molecular structure, mechanism of ac...

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Bibliographic Details
Main Authors: S. Bombardieri, U. Fiocco
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/237