A systematic summary and comparison of animal models for chemotherapy induced (peripheral) neuropathy (CIPN).

Despite the large amount of human and experimental studies no effective (prophylactic) treatment exists for chemotherapy induced peripheral neuropathy (CIPN), a disabling side effect of many cancer treatments. One of the underlying reasons for this could be that often the preclinical animal models u...

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Bibliographic Details
Main Authors: Suvarna Gadgil, Mehmet Ergün, Sandra A van den Heuvel, Selina E van der Wal, Gert Jan Scheffer, Carlijn R Hooijmans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221787