NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells

<p>Abstract</p> <p>Background</p> <p>Homeodomain proteins control fundamental cellular processes in development and in cancer if deregulated. Three members of the NK-like subfamily of homeobox genes (NKLs), TLX1, TLX3 and NKX2-5, are implicated in T-cell acute lymphobla...

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Main Authors: Drexler Hans G, Schmidt Christian A, Battmer Karin, Kaufmann Maren, Meyer Corinna, Grabarczyk Piotr, Przybylski Grzegorz K, Venturini Letizia, Nagel Stefan, Scherr Michaela, MacLeod Roderick AF
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/371