EMILIN2 regulates platelet activation, thrombus formation, and clot retraction.

Thrombosis, like other cardiovascular diseases, has a strong genetic component, with largely unknown determinants. EMILIN2, Elastin Microfibril Interface Located Protein2, was identified as a candidate gene for thrombosis in mouse and human quantitative trait loci studies. EMILIN2 is expressed durin...

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Bibliographic Details
Main Authors: Menggui Huang, Devaraja Sannaningaiah, Nan Zhao, Yanqing Gong, Jessica Grondolsky, Jane Hoover-Plow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319747?pdf=render