Nociceptive transmission to rat primary somatosensory cortex--comparison of sedative and analgesic effects.

CO(2)-laser C-fibre evoked cortical potentials (LCEPs) is a potentially useful animal model for studies of pain mechanisms. A potential confounding factor when assessing analgesic effects of systemically administered drugs using LCEP is sedation. This study aims to clarify: 1) the relation between l...

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Bibliographic Details
Main Authors: Marcus Granmo, Tanja Jensen, Jens Schouenborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3540052?pdf=render