Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.

Defective CFTR expression and function are detectable in blood monocytes: development of a new blood test for cystic fibrosis.

<h4>Background</h4>Evaluation of cystic fibrosis transmembrane conductance regulator (CFTR) functional activity to assess new therapies and define diagnosis of cystic fibrosis (CF) is cumbersome. It is known that leukocytes express detectable levels of CFTR but the molecule has not been...

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Bibliographic Details
Main Authors: Claudio Sorio, Mario Buffelli, Chiara Angiari, Michele Ettorre, Jan Johansson, Marzia Vezzalini, Laura Viviani, Mario Ricciardi, Genny Verzè, Baroukh Maurice Assael, Paola Melotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21811577/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21811577/?tool=EBI

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