Targeting the signaling pathway of acylation stimulating protein

Acylation stimulating protein (ASP; C3adesArg) stimulates triglyceride synthesis (TGS) and glucose transport in preadipocytes/adipocytes through C5L2, a G-protein-coupled receptor. Here, ASP signaling is compared with insulin in 3T3-L1 cells. ASP stimulation is not Gαs or Gαi mediated (pertussis and...

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Bibliographic Details
Main Authors: Magdalena Maslowska, Helen Legakis, Farzad Assadi, Katherine Cianflone
Format: Article
Language:English
Published: Elsevier 2006-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752033618X