Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer

Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer

Cancer stem cells (CSCs) present chemo-resistance mechanisms contributing to tumour maintenance and recurrence, making their targeting of utmost importance in gastric cancer (GC) therapy. The Hippo pathway has been implicated in gastric CSC properties and was shown to be regulated by leukaemia inhib...

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Bibliographic Details
Main Authors: Lornella Seeneevassen, Julie Giraud, Silvia Molina-Castro, Elodie Sifré, Camille Tiffon, Clémentine Beauvoit, Cathy Staedel, Francis Mégraud, Philippe Lehours, Océane C.B. Martin, Hélène Boeuf, Pierre Dubus, Christine Varon
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
gastric carcinoma
GP190
LATS1/2
YAP
CD44
ALDH
Online Access:https://www.mdpi.com/2072-6694/12/8/2011

Internet

https://www.mdpi.com/2072-6694/12/8/2011

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