Protective effector memory CD4 T cells depend on ICOS for survival.

Protective effector memory CD4 T cells depend on ICOS for survival.

Memory CD4 T cells play a vital role in protection against re-infection by pathogens as diverse as helminthes or influenza viruses. Inducible costimulator (ICOS) is highly expressed on memory CD4 T cells and has been shown to augment proliferation and survival of activated CD4 T cells. However, the...

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Bibliographic Details
Main Authors: Tamson V Moore, Bryan S Clay, Caroline M Ferreira, Jesse W Williams, Magdalena Rogozinska, Judy L Cannon, Rebecca A Shilling, Amanda L Marzo, Anne I Sperling
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3041765?pdf=render

Internet

http://europepmc.org/articles/PMC3041765?pdf=render

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