RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

The development of cardiac dysfunction caused by microbial infection predicts high mortality in sepsis patients. Specialized pro-resolving mediators (SPMs) mediate resolution of inflammation in many inflammatory diseases, and are differentially expressed in plasma of sepsis patients. Here, we invest...

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Bibliographic Details
Main Authors: Jianmin Chen, Gareth S. D. Purvis, Debora Collotta, Sura Al Zoubi, Michelle A. Sugimoto, Antonino Cacace, Lukas Martin, Roman A. Colas, Massimo Collino, Jesmond Dalli, Christoph Thiemermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Immunology
Subjects:
polymicrobial sepsis
resolvin E1
bacterial clearance
immune response
cardiomyopathy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02080/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02080/full

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