Optimizing imaging depth of anisotropic scattering tissues with polarization engineered second harmonic generation microscopy

Connective tissues in vertebrates consist of many anisotropic structures formed by collagen and muscle fibers, which could also generate intense second harmonic (SH). In SHG based tissue imaging, the incident light, when subjected to birefringence and scattering, would lead to a rapid decrement in i...

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Bibliographic Details
Main Authors: Shuai-Yan Chen, Zhi-Teng Su, Dan-Jae Lin, Ming-Xin Lee, Ming-Che Chan, Subir Das, Fu-Jen Kao, Guan-Yu Zhuo
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Results in Physics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211379721007427