Using S. cerevisiae as a Model System to Investigate V. cholerae VopX-Host Cell Protein Interactions and Phenotypes

Most pathogenic, non-O1/non-O139 serogroup Vibrio cholerae strains cause diarrheal disease in the absence of cholera toxin. Instead, many use Type 3 Secretion System (T3SS) mediated mechanisms to disrupt host cell homeostasis. We identified a T3SS effector protein, VopX, which is translocated into m...

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Bibliographic Details
Main Authors: Christopher H. Seward, Alexander Manzella, Ashfaqul Alam, J. Scott Butler, Michelle Dziejman
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Toxins
Subjects:
Online Access:http://www.mdpi.com/2072-6651/7/10/4099