Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities

Alkyl-Resorcinol Derivatives as Inhibitors of GDP-Mannose Pyrophosphorylase with Antileishmanial Activities

Leishmaniasis is a vector-borne disease caused by the protozoan parasite <i>Leishmania</i> found in tropical and sub-tropical areas, affecting 12 million people around the world. Only few treatments are available against this disease and all of them present issues of toxicity and/or resi...

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Bibliographic Details
Main Authors: Hélène Levaique, Olivier Pamlard, Cécile Apel, Jérôme Bignon, Margaux Arriola, Robin Kuhner, Khalijah Awang, Philippe M. Loiseau, Marc Litaudon, Sébastien Pomel
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
<i>Leishmania</i>
therapeutic target
GDP-Mannose pyrophosphorylase
natural products
alkyl-resorcinol
Online Access:https://www.mdpi.com/1420-3049/26/6/1551

Internet

https://www.mdpi.com/1420-3049/26/6/1551

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